| 摘要 |
<p>Novel salts formed between two active drug substances, wherein the first drug substance is an NSAID drug substance containing a carboxylic acid group and the second drug substance contains an amine group and is a local anaesthetic or selected from the group consisting of non-opioid analgesics, antipsychotics, antidepressants, narcotic antagonists and local anaesthetics. Such salts that are poorly soluble in tissue fluids are feasible for injectable prolonged release formulations where the NSAID additionally to minimize pain and tissue reaction at the site of administration.</p> |
