A NOVEL G PROTEIN-COUPLED RECEPTOR, GAVE2

摘要

Novel GAVE2 polypeptides, proteins and nucleic acid molecules are provided. In addition to isolated, full-length GAVE2 proteins, isolated GAVE2 fusion proteins, antigenic peptides and anti-GAVE2 antibodies are taught. GAVE2, recombinant expression vectors, host cells into that the expression vectors have been introduced and non-human transgenic animals in that a GAVE2 gene has been introduced or disrupted are taught. Diagnostic, screening and therapeutic methods utilizing compositions of the invention also are provided. GAVE2 is expressed in small intestine.