| 摘要 |
A method for early diagnosis of neoplasia and for estimating the risk of developing, and/or spreading, of malignant neoplasia, comprising by quantitative or qualitative detection of autoantibodies against specific gangliosides, is new. Method for early diagnosis of neoplasia and for estimating the risk of developing, and/or spreading, of malignant neoplasia comprises determining the presence and amount of antibodies (Ab): (i) that bind to ganglioside structures (GS) and to antigenic structures that mimic GS; or (ii) whose presence (and/or presence at a significantly higher level than in normal subjects) is correlated with high sensitivity to presence and/or risk of malignant neoplasia. Ab are determined in a highly sensitive assay.
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