POLYPEPTIDE ANTIGEN INDUCING HIV NEUTRALIZING ANTIBODIES

摘要

The invention concerns a polypeptide of formula N-L-C, wherein N represents the sequence of amino acids 25-81 of gp41, C represents the sequence of amino acids 112-157 of gp41, and L represents the flexible linker comprising 2 to 30 amino acids, for preparing a pharmaceutical composition for inducing antibodies neutralizing HIV primary isolates.