2 pyridyl 3,4 dihydroisoquinolines antipyretics

摘要

2 Pyridyl 3,4 dihydroisoquinolines antipyretics antiphlogistics. F3A. Of formula (I): (where R1 and R2 = alkyl (1-3C); R3 = H, CH3 or halogen; R4 and R5 = H or CH3), may be prepared by any of the following routes: (where one of X and Y represents H and the other represents OH, which may be esterified, or halogen, or X and Y together form a bond) (where R1 = -CH2R1') (where R1' and R2' = H or lower alkyl such that R'1=R1 and R2=-CH2R2' or R2=R2' and R1=-CH2R1') (where R5=-CH2R5')