| 发明名称 |
DENGUE TETRAVALENT VACCINE CONTAINING A COMMON 30 NUCLEOTIDEDELETION IN THE 3'-UTR OF DENGUE TYPES 1,2,3, AND 4, OR ANTIGENIC CHIMERIC DENGUE VIRUSES 1,2,3, AND 4 |
| 摘要 |
The invention relates to a dengue virus tetravalent vaccine containing a common 30 nucleotide deletion (.DELTA.30) in the 3'-untranslated region of t he genome of dengue virus serotypes 1, 2, 3, and 4, or antigenic chimeric dengu e viruses of serotypes 1, 2, 3, and 4. |
| 申请公布号 |
CA2483653(A1) |
申请公布日期 |
2003.11.13 |
| 申请号 |
CA20032483653 |
申请日期 |
2003.04.25 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SE CRE |
发明人 |
MARKOFF, LEWIS;MURPHY, BRIAN R.;FALGOUT, BARRY;BLANEY, JOSEPH;HANLEY, KATHRYN;WHITEHEAD, STEPHEN S. |
| 分类号 |
C12N15/09;A61K;A61K31/7088;A61K38/00;A61K39/00;A61K39/12;A61K39/295;A61K39/42;A61P31/14;C07H21/00;C07H21/04;C12N7/00;C12N7/04 |
主分类号 |
C12N15/09 |
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