发明名称 NOVEL AMIDE DERIVATIVES OR SALTS THEREOF
摘要 It is intended to provide compounds of the following general formula (I) which are glycogen phosphorylase inhibitors and useful as remedies and preventives for insulin-dependent diabetes (type 1 diabetes), insulin-independent diabetes (type 2 diabetes), insulin resistant disease and obesity. Namely, glycogen phosphorylase inhibitors characterized by having an indole ring, etc. bonded to a ring A (an aryl ring or an aromatic heterocycle) via an amide bond and the ring A having a hydroxyethylene moiety as a substituent. It is still preferable that the glycogen phosphorylase inhibitors are characterized in that the above-described ring A has a dihydroxyethylene moiety as a substituent. (I) wherein each substituent is as defined in claim 1.
申请公布号 WO03091213(A1) 申请公布日期 2003.11.06
申请号 WO2003JP05198 申请日期 2003.04.23
申请人 YAMANOUCHI PHARMACEUTICAL CO., LTD.;ONDA, KENICHI;SUZUKI, TAKAYUKI;SHIRAKI, RYOTA;YONETOKU, YASUHIRO;OGIYAMA, TAKASHI;MARUYAMA, TATSUYA;MOMOSE, KAZUHIRO 发明人 ONDA, KENICHI;SUZUKI, TAKAYUKI;SHIRAKI, RYOTA;YONETOKU, YASUHIRO;OGIYAMA, TAKASHI;MARUYAMA, TATSUYA;MOMOSE, KAZUHIRO
分类号 A61K31/404;A61K31/407;A61K31/427;A61K31/4439;A61K31/497;A61K31/506;A61P3/04;A61P3/10;A61P43/00;C07D209/42;(IPC1-7):C07D209/42;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D417/12;C07D495/04;A61K31/443 主分类号 A61K31/404
代理机构 代理人
主权项
地址