发明名称 Fused bicyclic amide compounds and medicinal use thereof
摘要 The present invention provides a compound represented by the formula (I) wherein ring A is benzene, cyclohexane, pyridine, piperidine or a derivative thereof, imidazole or a derivative thereof and the like, ring B is benzene, cyclohexane, pyrrole or a derivative thereof, furan, thiophene and the like, R<1>, R<2 >and R<3 >are each hydrogen, alkyl, halogen, hydroxyl group, alkoxy and the like, W is hydrogen, alkyl or hydroxycarbonylalkyl, X is halogen, cyano, nitro and the like, X' is hydrogen, halogen and the like, and Y is alkyl, hydroxyalkyl, hydroxycarbonylalkyl, aminoalkyl and the like, a salt thereof, and a pharmaceutical agent containing the compound. The compound of the present invention shows a superior inhibitory effect on the proliferation of activated lymphocyte and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.
申请公布号 US2003203909(A1) 申请公布日期 2003.10.30
申请号 US20030344261 申请日期 2003.04.29
申请人 USHIO HIROYUKI;NAITO YOUICHIRO;SUGIYAMA NAOKI;KAWAGUCHI TAKAFUMI;OHTSUKI MAKIO;CHIBA KENJI 发明人 USHIO HIROYUKI;NAITO YOUICHIRO;SUGIYAMA NAOKI;KAWAGUCHI TAKAFUMI;OHTSUKI MAKIO;CHIBA KENJI
分类号 A61K31/015;A61K31/343;A61K31/381;A61K31/404;A61K31/4184;A61K31/4365;A61K31/4704;A61K31/498;A61P29/00;A61P37/00;A61P43/00;C07D209/42;C07D211/46;C07D307/85;C07D307/86;C07D333/70;C07D405/12;C07D409/12;C07D495/04;(IPC1-7):A61K31/498;A61K31/474;A61K31/47;A61K31/417;A61K31/418 主分类号 A61K31/015
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