发明名称 |
METHODS FOR GENE DISRUPTION AND USES THEREOF |
摘要 |
The present invention relates to compositions and methods for in-frame disruption of a gene sequence by homologous recombination. The present invention may be used in certain embodiments to disrupt a gene without causing any downstream effects on non-target sequences. In certain embodiments, the inventive methods may be used to identify and/or characterize products encoded by essential genes, conditionally essential genes, and non-essential genes. |
申请公布号 |
WO03010333(A3) |
申请公布日期 |
2003.10.30 |
申请号 |
WO2002CA01160 |
申请日期 |
2002.07.24 |
申请人 |
AFFINIUM PHARMACEUTICALS INC.;AWREY, DONALD, E.;GREENBLATT, JACK |
发明人 |
AWREY, DONALD, E.;GREENBLATT, JACK |
分类号 |
C12N1/21;C12N5/06;C12N15/09;C12N15/65;C12N15/74;C12N15/87;C12N15/90;C12Q1/68;G01N33/48;G01N33/50;G06F19/00 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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