| 摘要 |
PCT No. PCT/SE96/01603 Sec. 371 Date Jan. 23, 1997 Sec. 102(e) Date Jan. 23, 1997 PCT Filed Dec. 5, 1996 PCT Pub. No. WO97/22603 PCT Pub. Date Jun. 26, 1997A process for the manufacture of omeprazole from pyrmethyl alcohol via pyrmethyl chloride and pyrmetazole characterized in that the whole reaction sequence is carried out without any isolation or purification of intermediates. Further that the reaction is carried out in a main solvent system common for the whole reaction sequence and inert to the reactants formed during the process and used in the process. The process according to the present invention may also include an additional purification step. |
