| 摘要 |
<p>An apparatus (30) and method of using the apparatus (30) to prepare a biocompatible biodegradable matrix capable of supporting cells to form an implantable or engraftable surgical device. A matrix-forming fluid is contained within a chamber (75) defined by top (51 b) and bottom (51 c) surfaces of a thermally conductive material and spacers defining the thickness of the matrix. The chamber (75) is then cooled to freeze the solution at a controlled rate, resulting in a matrix with a desired and uniform thickness having symmetric and uniform reticulations. The apparatus (75) and method reproducibly forms such a matrix, which may be populated with cells for transplantation and engraftment into a wound.</p> |
