It has been found that nonimmunosuppressive, cyclophilin-binding cyclosporins are useful in the treatment and prevention of AIDS and AIDS-related disorders. Such cyclosporins include novel Ciclosporin derivatives modified at the 4- and/or 5-positions.
申请公布号
CA2054590(C)
申请公布日期
2003.09.16
申请号
CA19912054590
申请日期
1991.10.31
申请人
KO, SOO Y.;KOBEL, HANS;ROSENWIRTH, BRIGITTE;SEEBACH, DIETER;TRABER, RENE P.;WENGER, ROLAND;BOLLINGER, PIETRO
发明人
KO, SOO Y.;KOBEL, HANS;ROSENWIRTH, BRIGITTE;SEEBACH, DIETER;TRABER, RENE P.;WENGER, ROLAND;BOLLINGER, PIETRO