摘要 |
The present invention provides humanized, chimeric and human anti-CD74 antibodies, CD74 antibody fusion proteins, immunoconjugates, vaccines and bispecific that bind to CD74, the major histocompatibility complex (MHC) class-II invariant chain, Ii, which is useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies, other malignancies in which the cells are reactive with CD74, and autoimmune diseases, and methods of treatment and diagnosis. |
申请人 |
IMMUNOMEDICS, INC.;MCCALL, JOHN, DOUGLAS |
发明人 |
HANSEN, HANS;LEUNG, SHUI-ON;QU, ZHENGXING;GOLDENBERG, DAVID, M. |