METHOD FOR INCREASING THE PRODUCTION OF A SECONDARY METABOLITE IN A MICROORGANISM BY INTRODUCING MUTATIONS THAT CONFER ANTIBIOTIC-RESISTANCE
摘要
This invention relates to a method for increasing the productivity of the secondary metabolite in a micro-organism, for example, the improvement of antibiotic producers by conferring drug-resistant mutations to micro-organisms.
申请公布号
WO02079453(A3)
申请公布日期
2003.08.28
申请号
WO2002JP03161
申请日期
2002.03.29
申请人
THE NATIONAL FOOD RESEARCH INSTITUTE;OCHI, KOZO;FUJISAWA PHARMACEUTICAL CO., LTD.;HU, HAIFENG;HINO, MOTOHIRO;FUJIE, AKIHIKO;MURAMATSU, HIDEYUKI