发明名称 |
3-ALKANOYLAMINO-PROPIONIC ACID DERIVATIVES USED AS INHIBITORS OF INTEGRIN AVSS6 |
摘要 |
The invention relates to novel biphenyl derivatives of general formula (I), in which R1, R1', R1" R2, R2' R3 and n are defined as per claim 1, to their stereoisomers and their physiologically acceptable salts or solvates. Said derivatives are novel integrin inhibitors, which preferably inhibit the av.beta.6 integrin receptor. The novel compounds can be used, in particular, as medicaments.
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申请公布号 |
CA2475930(A1) |
申请公布日期 |
2003.08.14 |
申请号 |
CA20032475930 |
申请日期 |
2003.01.15 |
申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG |
发明人 |
SCHADT, OLIVER;STAEHLE, WOLFGANG;JONCZYK, ALFRED;GOODMAN, SIMON |
分类号 |
A61K31/44;A61K31/4402;A61P1/04;A61P1/18;A61P3/14;A61P7/02;A61P9/00;A61P9/10;A61P11/00;A61P13/02;A61P13/12;A61P15/00;A61P17/00;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P27/02;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;C07D213/74;(IPC1-7):C07D213/74;A61K31/440 |
主分类号 |
A61K31/44 |
代理机构 |
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