发明名称 |
Evolution of whole cells and organisms by recursive sequence recombination |
摘要 |
The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites
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申请公布号 |
US2003148309(A1) |
申请公布日期 |
2003.08.07 |
申请号 |
US20020194686 |
申请日期 |
2002.07.11 |
申请人 |
MAXYGEN, INC. |
发明人 |
DEL CARDAYRE STEPHEN;TOBIN MATTHEW;STEMMER WILLEM P. C.;NESS JON E.;MINSHULL JEREMY;PATTEN PHILLIP;SUBRAMANIAN VENKITESWATAN;CASTLE LINDA A.;KREBBER CLAUS M.;BASS STEVEN;ZHANG YING-XIN;COX TONY;HUISMAN GJALT;YUAN LING;AFFHOLTER JOSEPH A. |
分类号 |
C07K14/245;C12N15/10;C12N15/82;C12P17/16;C12Q1/68;(IPC1-7):C12Q1/68;C12N15/85;C12N5/00 |
主分类号 |
C07K14/245 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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