发明名称 |
METHOD FOR INHIBITING EXPRESSION OF GENE |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for inhibiting the expression of a target gene by a double-stranded polynucleotide composed of a DNA and an RNA. <P>SOLUTION: The expression of a target gene is inhibited by preparing a double-stranded polynucleotide composed of a DNA and an RNA having a sequence essentially the same as at least a part of the base sequence of the target gene and introducing the polynucleotide into a cell, tissue or individual body. The double-stranded polynucleotide is stabilized and the synthesis cost is reduced by the inclusion of the DNA. <P>COPYRIGHT: (C)2003,JPO |
申请公布号 |
JP2003219893(A) |
申请公布日期 |
2003.08.05 |
申请号 |
JP20020337903 |
申请日期 |
2002.11.21 |
申请人 |
MITSUBISHI CHEMICALS CORP |
发明人 |
TEI KUMIKO;KAJI TAKAHIDE;UEDA TATSU;SAIGO KAORU |
分类号 |
G01N33/50;A61K31/7088;A61K31/713;A61K48/00;A61P3/10;A61P17/00;A61P25/28;A61P35/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12Q1/02;C12Q1/68;G01N33/15 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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