| 发明名称 |
ANTISENSE MODULATION OF X-LINKED INHIBITOR OF APOPTOSIS EXPRESSION |
| 摘要 |
<p>Antisense compounds, compositions and methods are provided for modulating the expression of X-linked inhibitor of apoptosis. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding X-linked inhibitor of apoptosis. Methods of using these compounds for modulation of X-linked inhibitor of apoptosis expression and for treatment of diseases associated with expression of X-linked inhibitor of apoptosis are provided.</p> |
| 申请公布号 |
EP1218395(A4) |
申请公布日期 |
2003.07.30 |
| 申请号 |
EP20000904275 |
申请日期 |
2000.01.11 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
BENNETT, C., FRANK;ACKERMANN, ELIZABETH, J.;COWSERT, LEX, M. |
| 分类号 |
C12N15/09;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P15/00;A61P29/00;A61P35/00;C12N15/113;C12N15/15;(IPC1-7):C07H21/04;C12Q1/68;C12N15/00 |
主分类号 |
C12N15/09 |
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