发明名称 TARGETED RETROGRADE GENE DELIVERY TO MOTOR NEURONS
摘要 <p>Methods are disclosed for delivering a heterologous gene to a cell body of a neuron by contacting either the synaptic portion of a neuron, for example or a muscle tissue innervated by the neuron, with a viral vector comprising a heterologous gene, wherein the viral vector enters said neuron and is retrogradely moved to the cell body. Additionally, methods for expressing secreted proteins from a nerve cell body as well as methods for treating neurodegenerative disorders are described.</p>
申请公布号 WO2003055983(A2) 申请公布日期 2003.07.10
申请号 US2002041194 申请日期 2002.12.20
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