发明名称 |
OPTINEURIN AND GLAUCOMA |
摘要 |
Methods of diagnosis of the presence or absence of optineuxin-associated glaucoma.or of an optinewinwassociated increased risk of glaucoma are described, in which a sample is tested for the presence of certain mutations in the gene, optineurin, that are associated with glaucoma or with an increased risk of glaucoma, as are methods in which a sample is tested for the presence of alterations in expression of optineurin polypeptide, as well as methods in which a sample is tested for the presence of alterations in optineurin polypeptide activity. Also described are methods of therapy of glaucoma, utilizing optineurin therapeutic agents.
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申请公布号 |
CA2471452(A1) |
申请公布日期 |
2003.07.10 |
申请号 |
CA20022471452 |
申请日期 |
2002.12.18 |
申请人 |
UNIVERSITY OF CONNECTICUT;ST. GEORGE'S ENTERPRISES LIMITED |
发明人 |
CHILD, ANNE HAWTHORNE;REZAIE, TAYEBEH;SARFARAZI, MANSOOR |
分类号 |
A47G25/10;A47G25/48;B24D3/28;B24D3/34;B24D7/00;C08L61/06;C08L61/14;C09C1/40;C09C3/12;C09K3/14;C12Q1/68;(IPC1-7):C12Q1/68 |
主分类号 |
A47G25/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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