发明名称 |
Verfahren und Vorrichtung zur Bestimmung eines Lichttransportparameters und eines Analyten in einer biologischen Matrix |
摘要 |
The invention relates to a method for selectively determining the index of dispersion mu <sb>s </sb>in a biological dispersion matrix, especially for the non-invasive determination of the concentration of glucose in the skin, with the aid of detection measuring, whereby respective light is radiated as a primary light (9) in the biological matrix (5) and measurement occurs for an intensity measuring value of exposed secondary light (12) exiting from a detection point (33-40), which is disposed at various measuring distances ( rho ) from the respective point of radiation (10) during said detection measurements. In order to improve the quality and selectivity of the determination of mu <sb>s</sb>, the primary light is radiated by means of a contacting light guiding element at an oblique angle of between 5 DEG and 85 DEG . At least two detection measurements of the measuring interval ( rho ) between the respective radiation point (10) and the respective detection point (33-40) corresponds to a maximum five fold value of the average path length of the propagating light in the biological matrix.
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申请公布号 |
DE10163972(A1) |
申请公布日期 |
2003.07.10 |
申请号 |
DE20011063972 |
申请日期 |
2001.12.22 |
申请人 |
ROCHE DIAGNOSTICS GMBH |
发明人 |
KRAEMER, UWE;HEIN, HEINZ-MICHAEL;HERMANN, MARCUS |
分类号 |
G01N21/17;A61B5/00;A61B5/145;A61B5/1455;G01N21/49;(IPC1-7):G01N21/47 |
主分类号 |
G01N21/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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