发明名称 A NOVEL SCREENING METHOD FOR MOLECULAR ANTAGONIST USING FLOW-CYTOMETRY
摘要 The present invention relates to a robust and sensitive assay system utilizing synthetic spherical structures in place of cells for a FACS analysis. The method and system detects the affinity and neutralization activity of a biological molecule without interference from growth medium or cell supernatants. The systems associated with these methods allow high-throughput screening of assays for, in particular, neutralizing monoclonal antibodies.
申请公布号 WO03056301(A2) 申请公布日期 2003.07.10
申请号 WO2002US40335 申请日期 2002.12.18
申请人 CENTOCOR, INC. 发明人 PERITT, DAVID;SEIDEMAN, DAVID
分类号 G01N33/543;G01N33/68 主分类号 G01N33/543
代理机构 代理人
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