METERED DOSE INHALER FOR ALBUTEROL

摘要

A process for preparation of a metered dose inhaler suitable for containing a drug formulation having reduced susceptibility to drug adhesion to the inner surfaces which process comprises: i) providing a strengthened aluminium or aluminium alloy metered dose inhaler can capable of withstanding stressful coating and curing conditions; ii) providing a formulation of a coating polymer comprising one or more fluorocarbon polymers optionally in combination with one or more non-fluorocarbon polymers; iii) coating said can on its inside with said formulation of coating polymer; and iv) curing the coating on the can.