发明名称 Hydroxypropylamines
摘要 Disclosed are compounds of formula I: and the pharmaceutically acceptable salts thereof wherein the variables RN, R1, R2, R3, RP and RC are defined herein. These compounds are useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
申请公布号 US2003125365(A1) 申请公布日期 2003.07.03
申请号 US20020264707 申请日期 2002.10.04
申请人 FISHER JED F.;JACOBS JON S.;SHERER BRIAN 发明人 FISHER JED F.;JACOBS JON S.;SHERER BRIAN
分类号 A61P25/16;A61P25/28;C07C215/28;C07C233/78;C07C311/17;C07D263/32;(IPC1-7):A61K31/421;A61K31/165;C07D263/02;C07C311/15 主分类号 A61P25/16
代理机构 代理人
主权项
地址