Method of screening drug for hepatitis C

摘要

Hepatitis C virus-biding protein has been found to be a 40S ribosomal protein S5 composing a 40S ribosomal subunit of an eukaryote. On the basis of this finding, there is provided a method for screening test substances for a substance exhibiting anti-hepatitis-C-virus activity, through detection of inhibitory activity of the substance against binding between an IRES of a hepatitis C virus gene and a 40S ribosomal protein S5.