| 发明名称 |
3-CYANOQUINOLINES AS INHIBITORS OF EGF-R AND HER2 KINASES |
| 摘要 |
This invention provides compounds of Formula (I), represented by the structure wherein G1, G2, G3, G4, Z, X and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of polycystic kidney disease.
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| 申请公布号 |
WO03050090(A1) |
申请公布日期 |
2003.06.19 |
| 申请号 |
WO2002US37918 |
申请日期 |
2002.11.26 |
| 申请人 |
WYETH HOLDINGS CORPORATION |
发明人 |
WISSNER, ALLAN;TSOU, HWEI-RU;FLOYD, MIDDLETON, BRAWNER, JR.;JOHNSON, BERNARD, DEAN;OVERBEEK-KLUMPERS, ELSEBE, GERALDINE |
| 分类号 |
A61K31/4706;A61K31/4709;A61P1/00;A61P1/02;A61P11/00;A61P13/10;A61P13/12;A61P15/00;A61P35/00;C07D215/54;C07D215/56;C07D401/14;C07D417/12;(IPC1-7):C07D215/54;A61K31/47 |
主分类号 |
A61K31/4706 |
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