摘要 |
<p>The present invention relates to isolated calpain activator peptides derived from the sequences of subdomains A and C of any of the four [inhibitory] domains of calpastatins and any functional homologues or variant thereof. Peptides for use in medicine are also provided. The present invention further relates to compositions, reagent kits and research tools comprising said peptides, as well as methods for activating and/or sensitizing calpain.</p> |