发明名称 |
Method for detection of inflammatory processes |
摘要 |
The present invention is based on the surprising observation, that a high degree of expression of certain distinct Genes in peripheral blood mononuclear cells is associated with in inflammatory process with a higher probability than it is the case for other Genes. Therefore, the present invention provides a method for diagnosis of an inflammatory process comprising monitoring expression levels of 4-6 selected targets in peripheral blood mononuclear cells as compared to expression levels of said selected targets in peripheral blood mononuclear cells in healthy individuals, characterized in that over-expression or repression of the majority of said selected Genes is indicative for an inflammatory process.
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申请公布号 |
EP1319717(A1) |
申请公布日期 |
2003.06.18 |
申请号 |
EP20010129229 |
申请日期 |
2001.12.11 |
申请人 |
ROCHE DIAGNOSTICS GMBH;F. HOFFMANN-LA ROCHE AG |
发明人 |
MEUER, STEFAN;GIESE, THOMAS |
分类号 |
C12N15/09;C12Q1/68;(IPC1-7):C12Q1/68;C12Q1/70 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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