发明名称 |
Human ex vivo immune system |
摘要 |
The present invention provides cultured immune system cells and methods of producing same. The method comprises culturing stromal cells and hemopoietic stem cells or in a chamber having a scaffolding covered or surrounded with culture medium, wherein the scaffolding allows for hemopoietic stem cells and stromal cells to have cell to cell contacts in three dimensions. The subject immune system cells are useful for screening drugs which inhibit or stimulate the immune system. The subject immune system cells are also useful in treating diseases of the immune system.
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申请公布号 |
US2003109042(A1) |
申请公布日期 |
2003.06.12 |
申请号 |
US20020244653 |
申请日期 |
2002.09.16 |
申请人 |
WU J.H. DAVID;MANTALARIS ATHANASSIOS |
发明人 |
WU J.H. DAVID;MANTALARIS ATHANASSIOS |
分类号 |
G01N33/50;A61K48/00;A61P37/00;C07K16/00;C12M3/06;C12N5/02;C12N5/0789;C12N15/09;C12P21/08;C12Q1/68;G01N33/15;G01N33/569;(IPC1-7):C12N5/08 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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