发明名称 Antisense modulation of toll-like receptor 4 expression field of the invention
摘要 <p>Antisense compounds, compositions and methods are provided for modulating the expression of Toll-like receptor 4. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Toll-like receptor 4. Methods of using these compounds for modulation of Toll-like receptor 4 expression and for treatment of diseases associated with expression of Toll-like receptor 4 are provided.</p>
申请公布号 AU2002361620(A8) 申请公布日期 2003.06.10
申请号 AU20020361620 申请日期 2002.11.14
申请人 ISIS PHARMACEUTICALS, INC. 发明人 JAMES G. KARRAS;ERICH KOLLER
分类号 A61K38/00;C12N15/113;(IPC1-7):C12N5/00;A61K31/70;C12Q1/68;A01N43/04;C07H21/04 主分类号 A61K38/00
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