发明名称 |
Regulatable, catalytically active nucleic acids |
摘要 |
Compositions and methods are provided to make, isolate, characterize and use regulatable, catalytically active nucleic acids (RCANA). RCANA may be used for regulating gene expression and in assays to detect the presence of ligands or to detect activation by an effector of an RCANA bound to a solid support such as a chip or multi-well plate. Also disclosed are compositions and methods for automating the selection procedures of the present invention.
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申请公布号 |
US2003104520(A1) |
申请公布日期 |
2003.06.05 |
申请号 |
US20010883119 |
申请日期 |
2001.06.14 |
申请人 |
ELLINGTON ANDREW D.;HESSELBERTH JAY;MARSHALL KRISTIN A.;ROBERTSON MICHAEL P.;SOOTER LETHA;DAVIDSON ERIC;COX J. COLIN;REIDEL TIMOTHY |
发明人 |
ELLINGTON ANDREW D.;HESSELBERTH JAY;MARSHALL KRISTIN A.;ROBERTSON MICHAEL P.;SOOTER LETHA;DAVIDSON ERIC;COX J. COLIN;REIDEL TIMOTHY |
分类号 |
G01N33/53;A61K38/00;A61K48/00;C12M1/00;C12M1/38;C12N15/09;C12N15/113;C12Q1/02;C12Q1/68;G01N33/543;(IPC1-7):A61K38/08;A61K38/10;C07K7/08;C07K7/06;C07H21/04;C12P21/02;C12N5/06 |
主分类号 |
G01N33/53 |
代理机构 |
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地址 |
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