发明名称 Compositions and methods for highly efficient transfection
摘要 The invention encompasses a transfection complex comprising a polypeptide comprising the contiguous 29 amino acids: 6G's, 2F's, 2L's, 1W, 4R's, 2E's, 2N's, 3K's, 1T, 1S, 1A, 1Y, 1M, 1C, and 1I, and having additional cationic residues to provide a net number of positive charges of equal to or greater than 8, and an isolated nucleic acid, and methods of transfecting cells using this transfection complex. The invention also includes a polypeptide having an amino acid composition including these 29 amino acids, as well as mixtures of polypeptides in which this polypeptide is present.
申请公布号 US2003100496(A1) 申请公布日期 2003.05.29
申请号 US20020219626 申请日期 2002.08.15
申请人 HAINES ADRIAN MARK;PHILLIPS ROSS OWEN;WELSH JOHN HAMILTON;THATCHER DAVID ROBERT;IRVINE ALISTAIR SIMPSON;CRAIG ROGER KINGDON 发明人 HAINES ADRIAN MARK;PHILLIPS ROSS OWEN;WELSH JOHN HAMILTON;THATCHER DAVID ROBERT;IRVINE ALISTAIR SIMPSON;CRAIG ROGER KINGDON
分类号 A61K38/00;A61K39/00;A61K39/12;A61K39/145;A61K39/21;A61K39/29;A61K48/00;C07K14/00;C12N15/88;(IPC1-7):A61K48/00;A61K38/10;C07K7/08 主分类号 A61K38/00
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