发明名称 |
INJECTABLE PHARMACEUTICAL COMPOSITION FOR SYSTEMIC DELIVERY OF PHARMACOLOGICALLY ACTIVE COMPOUNDS COMPRISING MEDIUM CHAIN TRIGLYCERIDES |
摘要 |
The invention relates to novel pharmaceutical compositions for the systemic administration of pharmacologically active ingredients. The invention relates in particular to an injectable pharmaceutical composition comprising (a) a pharmacologically active ingredient in a solid phase, (b) a vehicle consisting substantially of polyol fatty acid esters with a degree of esterification of over 80%, and (c) a wetting agent consisting substantially of polyol fatty acid esters with a monoester proportion of over 60%. The inventive composition is used for the systemic administration of numerous pharmacologically active ingredients, whereby the ingredients are released from the pharmaceutical composition over a period of at least 12, preferably at least 24 hours. |
申请公布号 |
EP1313510(A2) |
申请公布日期 |
2003.05.28 |
申请号 |
EP20010983443 |
申请日期 |
2001.08.21 |
申请人 |
SCHWARZ PHARMA AG |
发明人 |
RIMPLER, STEPHAN;GRAPATIN, SABINE;KREIN, CLIFF;THELEN, MARKUS |
分类号 |
A61K9/00;A61K9/10;A61K31/198;A61K31/381;A61K38/28;A61K47/14;A61P25/08;A61P25/16;A61P25/18;(IPC1-7):A61K47/14 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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