发明名称 INJECTABLE PHARMACEUTICAL COMPOSITION FOR SYSTEMIC DELIVERY OF PHARMACOLOGICALLY ACTIVE COMPOUNDS COMPRISING MEDIUM CHAIN TRIGLYCERIDES
摘要 The invention relates to novel pharmaceutical compositions for the systemic administration of pharmacologically active ingredients. The invention relates in particular to an injectable pharmaceutical composition comprising (a) a pharmacologically active ingredient in a solid phase, (b) a vehicle consisting substantially of polyol fatty acid esters with a degree of esterification of over 80%, and (c) a wetting agent consisting substantially of polyol fatty acid esters with a monoester proportion of over 60%. The inventive composition is used for the systemic administration of numerous pharmacologically active ingredients, whereby the ingredients are released from the pharmaceutical composition over a period of at least 12, preferably at least 24 hours.
申请公布号 EP1313510(A2) 申请公布日期 2003.05.28
申请号 EP20010983443 申请日期 2001.08.21
申请人 SCHWARZ PHARMA AG 发明人 RIMPLER, STEPHAN;GRAPATIN, SABINE;KREIN, CLIFF;THELEN, MARKUS
分类号 A61K9/00;A61K9/10;A61K31/198;A61K31/381;A61K38/28;A61K47/14;A61P25/08;A61P25/16;A61P25/18;(IPC1-7):A61K47/14 主分类号 A61K9/00
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