发明名称 |
Etoposide analogs and methods of use thereof |
摘要 |
Etoposide analogs such as 4'-O-demethyl-4beta-[4''-(methyl-L-tyrosine-N-carbonyl)-anilino]-4-des oxy-podophyllotoxin (12) and 4'-O-demethyl-4beta-[4''-(methyl-L-tryptophan-N-carbonyl)-anilino]-4-d esoxypodophyllotoxin (13) are described, along with pharmaceutical formulations containing the same, methods of use thereof, and intermediates and methods of making the same
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申请公布号 |
US6566393(B1) |
申请公布日期 |
2003.05.20 |
申请号 |
US20020177147 |
申请日期 |
2002.06.21 |
申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
LEE KUO-HSIUNG;XIAO ZHIYAN;BASTOW KENNETH F. |
分类号 |
C07D493/04;C07D497/04;(IPC1-7):A61K31/335;A61K31/38 |
主分类号 |
C07D493/04 |
代理机构 |
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地址 |
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