| 发明名称 |
Diaminediols for the treatment of Alzheimer's disease |
| 摘要 |
The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
|
| 申请公布号 |
US2003083353(A1) |
申请公布日期 |
2003.05.01 |
| 申请号 |
US20020192625 |
申请日期 |
2002.07.10 |
| 申请人 |
SCHOSTAREZ HEINRICH JOSEF;CHRUSCIEL ROBERT A. |
发明人 |
SCHOSTAREZ HEINRICH JOSEF;CHRUSCIEL ROBERT A. |
| 分类号 |
C07D277/20;A61K31/166;A61K31/421;A61K31/426;A61K31/4406;A61P9/10;A61P25/28;A61P43/00;C07C235/84;C07C237/34;C07C255/44;C07C271/20;C07C321/16;C07C323/42;C07D213/82;C07D233/70;C07D263/34;C07D263/48;C07D277/56;(IPC1-7):C07D213/72;A61K31/44;A61K31/275;A61K31/325;A61K31/13;A61K31/135;A61K31/195 |
主分类号 |
C07D277/20 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
