| 发明名称 |
ENHANCEMENT OF ANTIBODY-CYTOKINE FUSION PROTEIN MEDIATED IMMUNE RESPONSES BY COMBINED TREATMENT WITH IMMUNOCYTOKINE UPTAKE ENHANCING AGENTS. |
| 摘要 |
<p>Disclosed are methods and compositions for treating tumors. Disclosed methods and compositions enhance the uptake of immunocytokines into tumors, and are based on a combination of an immunocytokine with an immunocytokine uptake enhancing agent. Disclosed methods and compositions are particularly useful for reducing tumor size and metastasis in a mammal.</p> |
| 申请公布号 |
MXPA02012734(A) |
申请公布日期 |
2003.04.25 |
| 申请号 |
MX2002PA12734 |
申请日期 |
2001.06.29 |
| 申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG |
发明人 |
GILLIES, STEPHEN, D. |
| 分类号 |
C12N15/09;A61K31/282;A61K31/337;A61K31/66;A61K31/675;A61K38/20;A61K39/395;A61K45/00;A61P35/00;A61P43/00;C07K16/30;C07K19/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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