发明名称 |
COMPOSITIONS COMPRISING D-CHIRO INOSITOL AND SULFONYLUREAS AND METHODS OF TREATMENT THEREOF |
摘要 |
The present invention provides compositions comprising therapeutically effective amounts of D-chiro-inositol and sulfonylureas. The present invention also provides methods to treat a subject with insulin resistance comprising administration of D-chiro-inositol and sulfonylurea, either as concurrent single agents or as a combined composition. In particular the methods of the present invention are useful in maintaining pancreatic beta cell function/viability and thus delay diabetes progression. The methods and compositions of the present invention are particularly efficacious in treating insulin resistant subjects with a fasting blood glucose level of less than or equal to 180 mg/dL. |
申请公布号 |
WO02094744(A3) |
申请公布日期 |
2003.04.24 |
申请号 |
WO2002US13614 |
申请日期 |
2002.05.01 |
申请人 |
INSMED INCORPORATED |
发明人 |
SLEEVI, MARK, C.;ALLAN, GEOFFREY |
分类号 |
A61K31/22;A61K31/366;A61K31/40;A61K31/7004;A61K45/06 |
主分类号 |
A61K31/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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