| 发明名称 |
Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors |
| 摘要 |
<p>Protein tyrosine kinase inhibitor compounds are described, as are methods for their preparation, pharmaceutical compositions including such compounds, and their use in medicine, for example in the treatment of cancer and psoriasis. In particular, the use of an inhibitor of both EGFR and erbB-2 in the treatment of a susceptible malignancy, such as cancer or a malignant tumour, is described.</p> |
| 申请公布号 |
EP1304110(A2) |
申请公布日期 |
2003.04.23 |
| 申请号 |
EP20020080417 |
申请日期 |
1997.07.11 |
| 申请人 |
GLAXO GROUP LIMITED |
发明人 |
COCKERILL, GEORGE STUART;CARTER, MALCOLM CLIVE;GUNTRIP, STEPHEN BARRY;SMITH, KATHRYN JANE |
| 分类号 |
A61P35/00;C07D215/00;A61K;A61K31/519;A61K31/5355;A61P17/16;A61P43/00;C07D;C07D209/08;C07D231/56;C07D235/08;C07D401/06;C07D407/12;C07D471/04;C07D493/08;C07D519/00 |
主分类号 |
A61P35/00 |
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