| 摘要 |
<p>The invention relates to compounds of formula (I), wherein R1 is -NR'R', wherein R' and R' are independently from each other lower alkyl, -(CH¿2?)n-C(O)NR?aRb¿, -(CH¿2?)n-heteroaryl, -(CH2)n-aryl, -(CH2)n-CN, -(CH2)n-O-lower alkyl or -(CH2)n-cycloalkyl, or R'and R' form together with the N-atom a five or six-membered none aromatic ring, which may contain one additional O or S heteroatom, and whose rings may be unsubstituted or substituted by one or two substituents, selected from the group consisting of lower alkyl, -C(O)NR?aRb¿ or -(CH¿2?)n-O-lower alkyl and R?aRb¿ are independently from each other hydrogen or lower alkyl; R2 is aryl or heteroaryl, unsubstituted or substituted ba lower alkyl or halogen; n is 0, 1, 2 or 3; and to their pharmaceutically acceptable salts. The compounds may be used in the treatment of diseases, associated with the adenosime A2 receptor.</p> |
