发明名称 5-METHOXY-8-ARYL-[1,2,4] TRIAZOLO [1,5-A] PYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS
摘要 The present application relates to compounds of the formula (I) wherein R1 i s hydrogen, halogen or lower alkoxy; R2 is hydrogen or is C(O)- lower alkyl or - C(0)-phenyl, wherein the phenyl ring is unsubstituted or substituted by one or two substituents, selected from the group, consisting of halogen, lower alko xy or trifluoromethyl, or is -C(O)-furanyl or -C(O)- thiophenyl, wherein the rings are unsubstituted or substituted by halogen; and to their pharmaceutically acceptable salts. The compounds may be used in the treatmen t of diseases associated with the adenosine A2 receptor.
申请公布号 CA2462801(A1) 申请公布日期 2003.04.17
申请号 CA20022462801 申请日期 2002.09.28
申请人 F. HOFFMANN-LA ROCHE AG 发明人 SCHMITT, SEBASTIEN;NETTEKOVEN, MATTHIAS HEINRICH
分类号 A61K31/437;A61P9/10;A61P11/06;A61P11/16;A61P25/00;A61P25/04;A61P25/08;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P37/08;A61P43/00;C07D471/04;(IPC1-7):C07D471/04 主分类号 A61K31/437
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