| 摘要 |
PROBLEM TO BE SOLVED: To obtain a microemulsion composition effective for especially reducing pruritus of patients suffering from atopic dermatitis and having good preservation stability even under severe conditions in relation to microemulsion compositions having excellent humectant and obstruction properties and suitable for application to wide ranges of the skin. SOLUTION: This microemulsion composition comprises an oily ingredient composed of vaseline in an amount of >=90 wt.% based on the total amount, lecithin, betaines and water and is obtained by treating the oily ingredient, lecithin, betaines and water with both a high-speed stirrer and a high-pressure homogenizer. The resultant microemulsion has <=300 nm particle diameter of the inner phase. Furthermore, one or more kinds of polyhydric alcohols selected from 1,3-butylene glycol, glycerol, diglycerin, polyethylene glycol and 1,2- pentanediol are formulated therein. |
