COMPOSITION CONTAINING PHELLINUS LINTEUS EXTRACT FOR PREVENTION OR TREATMENT OF DISEASE ASSOCIATED WITH INHIBITION OF INTERCELLULAR COMMUNICATION THROUGH GAP JUNCTIONAL AND UNBALANCE OF HOMEOSTAS

摘要

PURPOSE: A composition containing an extract of Phellinus linteus as an effective component is provided which effectively recovers the inhibition of gap junctional intercellular communication and the unbalance of homeostasis and thus can be used for prevention or treatment of disease associated therewith. CONSTITUTION: Phellinus linteus is extracted in ethanol or hot water under high pressure and a pharmaceutical composition for prevention or treatment of disease associated with the inhibition of gap junctional intercellular communication and the unbalance of homeostasis contains the Phellinus linteus extract and a pharmaceutically acceptable carrier. The effective dose of the pharmaceutical composition is 15 to 170mg/kg body weight/day. The disease associated with the inhibition of gap junctional intercellular communication and the unbalance of homeostasis is nervous system disorders containing diabetics, Charcot-Marie-Tooth disease type 1, blood related disorders containing spermatogenesis disorders, blood related disorders containing hypertension or epilepsia.