| 摘要 |
<p>This invention provides a device containing a compound of formula (I), wherein R represents a saturated or unsaturated C2-7 aliphatic acyl group optionally substituted by one or more halogen atoms, a hydroxy group, a Cl-6 alkoxy group, a carboxyl group, a C2-7 alkoxycarbonyl group, a 5 to 7-membered cycloalkyl group, a phenyl or naphthyl group; a C2-6 hydroxyalkyl group; an aliphatic acyloxyalkyl group having a C2-7 acyl group and a Cl-6 alkyl group; a Cl-6 alkyl group substituted by a Cl-6 alkoxy group, a carboxyl group, a C2-7 alkoxycarbonyl group, a C2-7 alkoxycarbonyl group substituted by a phenyl or naphthyl group, a carbamoyl group, a mono- or di-(Cl-6 alkyl)-substituted carbamoyl group or a cyano group; a benzoyl or naphthoyl group optionally substituted by one or more halogen atoms; a furoyl group or a pyridylcarbonyl group; and R1 represents a C l-6 alkyl group optionally substituted by one or more halogen atoms, a phenyl or a naphthyl group; the carbon atom marked '*' represents a carbon atom in (R)- configuration, (S)-configuration or a mixture thereof. The TTS is efficient in the treatment of urinary tract disorders, such as benign prostatic hypertrophy.</p> |
