| 摘要 |
<p>Benzimidazole derivatives represented by the following general formula (1), salts thereof; and drugs containing the same: (1) wherein R represents hydrogen or methoxy; and n is 0 or 1. Because of showing little difference in therapeutic effect among individuals based on the difference in CYP2C19 activity among individuals, the above compounds can establish an adequate therapeutic effect in the same administration dose on any patients. Moreover, they show little risk of interaction and cancer onset induced by CYP1A family. Therefore, these compounds are useful as remedies for digestive ulcer safely and surely exerting therapeutic effects.</p> |
