| 发明名称 |
PROCESS FOR THE PREPARATION OF A PIPERAZINE DERIVATIVE |
| 摘要 |
<p>(2R)-1-Ä3,5-bis(trifluoromethyl)benzoylÜ-4-Ä2-Ä(2S)-2- (methoxymethyl)morpholinoÜethylÜ-2-(3-hydroxy-4-methylbenzyl)piperazine dihydrochloride is obtained by debenzylating (2R)-4-benzyl-1-Ä3,5-bis(trifluoromethyl)-benzoylÜ-2-(3-hydroxy-4-meth ylbenzyl)piperazine, then N-alkylating and converting to hydrochloride.</p> |
| 申请公布号 |
EP1295882(A1) |
申请公布日期 |
2003.03.26 |
| 申请号 |
EP20010938576 |
申请日期 |
2001.06.08 |
| 申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
KOGA, KEIICHI;ORII, RYOKI;FUJII, YOSUKE;GOTO, SHUNSUKE;HIRABAYASHI, SATOSHI |
| 分类号 |
C07D241/04;C07D413/06;(IPC1-7):C07D413/06 |
主分类号 |
C07D241/04 |
| 代理机构 |
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