| 摘要 |
<p>The present invention relates to 3-(4,5,6,7-tetrahydroindol-2-ylmethylidene)-2-indolinone derivatives of formula I, wherein R1 R4 are defined herein, that inhibit kinases, in particular Src kinase, Pharmaceutical compositions comprising these compounds, methods of treating diseases mediated by kinase utilizing pharmaceutical compositions comprising these compounds, and methods of preparing them are also disclosed.</p> |
