发明名称 |
COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES |
摘要 |
<p>The compounds of the invention are compounds represented by the following general formula (1): <CHEM> wherein E represents one selected from the group consisting of a methylidyne group and a nitrilo group, R<1> represents one selected from the group consisting of optionally substituted aryl groups and optionally substituted heteroaryl groups, R<2> represents one selected from the group consisting of a hydrogen atom and alkyl groups, W<1> represents an amino acid residue, A represents one selected from the group consisting of a carbonyl group and a sulfonyl group, X<1> represents one selected from the group consisting of optionally substituted alkylene groups and optionally substituted alkenylene groups, and p represents 0 or 1; and their pharmacologically acceptable salts, which exhibit thrombopoietin-like activity.</p> |
申请公布号 |
EP1291341(A1) |
申请公布日期 |
2003.03.12 |
申请号 |
EP20010934428 |
申请日期 |
2001.05.30 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA |
发明人 |
FUJIWARA, SHINYA;OZAKI, TOMOKAZU;KOZONO, TOSHIRO;HATTORI, KUNIHIRO;ESAKI, TORU |
分类号 |
A61K38/00;A61P7/04;C07C237/22;C07D209/18;C07D213/78;C07D333/24;C07D333/34;(IPC1-7):C07C237/22 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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