NOVEL METHOD FOR SYNTHESIS OF (2S, 3AS, 7AS)-1-[(S)-ALANYL]-OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID DERIVATIVES AND USE FOR SYNTHESIS OF PERINDOPRIL

摘要

The invention concerns a method for industrial synthesis of compounds of formula (I), wherein: R1 represents a hydrogen atom or a linear or branched C1-C6 alkyl group or benzyl, and R2 represents a group protecting the amino function. The invention also concerns the use of same for industrial synthesis of perindopril of formula (II) and its pharmaceutically acceptable salts.