| 摘要 |
The invention provides a sustained release composition free of food effect comprising: (a) a core comprising verapamil; and (b) a functional coating comprising, based on the weight of the coating, from 30 to 80% of a gastroresistant polymer and from 10 to 40% of a hydrophilic silicon dioxide. The invention also provides a method for alleviating food effect in a verapamil pharmaceutical composition.
|
