VECTOR FOR SITE-SPECIFIC INTEGRATION OF HETEROLOGOUS DNA SEQUENCES INTO THE RDN A SITES OF METHYLOTROPHIC YEASTS
摘要
The present invention is related to plasmid vectors for site-specific integration of heterologous DNA sequences in multiple copies into metilotrophic yeasts. A process for the expression of recombinant proteins based on the use of the present vectors and microorganisms derived from transformation with the vectors of the present invention are also described.
申请公布号
WO03014363(A1)
申请公布日期
2003.02.20
申请号
WO2002IB03086
申请日期
2002.08.05
申请人
BIOANALISI CENTRO SUD S.N.C.;ROSSOLINI, GIAN, MARIA;RICCIO, MARIA, LETIZIA;GALEOTTI, CESIRA;POMPEI, RAFFAELLO